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Caspase inhibition decreases both platelet phosphatidylserine exposure and aggregation; Caspase inhibition of platelets.
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A critical role for thrombin in platelet aggregation under high shear stress .
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Antiplatelet drugs in ischemic stroke prevention: from monotherapy to combined treatment
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Recent advances in thrombotic thrombocytopenic purpura
Hematology (Am Soc Hematol Educ Program). 2004 Ene; 407(23) Sadler JE, Moake JL, Miyata T, George JN |
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Glycoprotein IIb/IIIa inhibition enhances platelet nitric oxide release.
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Pharmacodynamic profile of antiplatelet agents: marked differences between single versus costimulation with platelet activators.
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The state of platelets preserved in extracorporeal circulation with a glycoprotein IIb/IIIa inhibitor.
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Effects of lipid-esterified conjugated linoleic acid isomers on platelet function: evidence for stimulation of platelet phospholipase activity.
Biochim Biophys Acta. 2003 Dic; 1635(2-3):75-82. Al-Madaney MM, Kramer JK, Deng Z, Vanderhoek JY |
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Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release.
Cell. 2003 Dic; 115(7):851-62. Walther DJ, Peter JU, Winter S, Holtje M, Paulmann N, Grohmann M, Vowinckel J, Alamo-Bethencourt V, Wilhelm CS, Ahnert-Hilger G, Bader M. |
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Plaque Rupture, Lysophosphatidic Acid, and Thrombosis
Circulation. 2003 Dic; 108(6):641-3. no señalados |
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Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo
Blood. 2003 Dic; 102(12):4021-7. Epub 2003 Jul 31 Gruner S, Prostredna M, Schulte V, Krieg T, Eckes B, Brakebusch C, Nieswandt B |
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Thrombin activation of factor XI on activated platelets requires the interaction of factor XI and platelet glycoprotein Ibalpha with thrombin anion binding exosites I and II respectively.
J Biol Chem.. 2003 Nov; 278(48):48112-9. Epub 2003 Sep 10 Yun TH, Baglia FA, Myles T, Navaneetham D, Lopez JA, Walsh PN, Leung LL |
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SH2 domain containing inositol 5-phosphatases 1 and 2 in blood platelets: interaction and respective role in the control of phosphatidylinositol 3,4,5-trisphosphate level.
Biochem J. 2003 Nov; 376(Pt 1):199-207. Epub ahead of print Sep Giuriato S, Pesesse X, Bodin S, Sasaki T, Viala C, Marion E, Penninger J, Schurmans S, Erneux C, Payrastre B. |
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PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets.
Blood.. 2003 Nov; 102(10):3658-64. Epub 2003 Jul 31 Rathore V, Stapleton MA, Hillery CA, Montgomery RR, Nichols TC, Merricks EP, Newman DK, Newman PJ. |
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Physical proximity and functional interplay of PECAM-1 with the Fc receptor Fc{gamma}RIIA on the platelet plasma membrane.
Blood. 2003 Nov; 102(10):3637-45. Epub 2003 Jul 31 Thai LM, Ashman LK, Harbour SN, Hogarth PM, Jackson DE. |
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Src kinase activation by direct interaction with the integrin beta cytoplasmic domain.
Proc Natl Acad Sci U S A. 2003 Nov; 100(23):13298-302. Epub 2003 Oct 30 Arias-Salgado EG, Lizano S, Sarkar S, Brugge JS, Ginsberg MH, Shattil SJ. |
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G(13) is an essential mediator of platelet activation in hemostasis and thrombosis.
Nat Med. 2003 Nov; 9(11):1418-22. Epub 2003 Oct 5 Moers A, Nieswandt B, Massberg S, Wettschureck N, Gruner S, Konrad I, Schulte V, Aktas B, Gratacap MP, Simon MI, Gawaz M, Offermanns S. |
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Effect of cellular and receptor activation on the extent of integrin alphaIIbbeta3 internalization.
J Thromb Haemost. 2003 Nov; 1(11):2404-10. Schober JM, Lam SC, Wencel-Drake JD. |
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H2O2-Induced Platelet Aggregation and Increase in Intracellular Ca2+ Concentration Are Blocked by Inhibitors of Intracellular Signaling.
Biochemistry (Mosc. 2003 Nov; 68(11):1210-6. Loiko EN, Samal AB, Shulyakovskaya SM. |
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AMP-activated protein kinase (AMPK) regulates the insulin-induced activation of the nitric oxide synthase in human platelets.
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